The Heart of Cape Town Museum – A Personal Experience (Part 1)

There are moments in life that make a deep impression – times when you are very young and don’t remember much about an event but you just recall vividly that there was something very important happening in the world around you at the time.

For me, such moments include the assassination of President Kennedy, the first moon landing, The Beatles’ first live performance on TV and among this eclectic mix – the news of the first heart transplant and the name Christiaan Barnard.

Years later, May 20th 2015, having followed a career in Life Sciences and medical research, I was travelling in South Africa and I found myself at the Heart of Cape Town Museum; an unforgettable experience I’d like to share with you.

Setting the Scene

Christiaan Barnard in his office

Christiaan Barnard (1922-2001) in his office in 1967

Picture, as I did: 1967 and a young charismatic doctor is beaming with a media-friendly smile. It follows years of hard work; tenacity and daring that lead him to carry out the first heart transplant – ‘a surgical feat that created a new medical era’. Barnard’s accomplishment brought South Africa and the University of Cape Town unprecedented international attention.

The Story – a dramatic series of events in medical history

After years of preparation, a surgical team was on standby for the appropriate circumstances. December 2nd 1967, following a tragic car accident, the clock starts. There is a donor, Denise Darvall, and there is a recipient, Louis Washkansky. Picture the two adjacent operating theatres, the technical skills and the subsequent international media coverage in which this was hailed as a breakthrough in organ transplant surgery and the start of a new medical era.

The donor heart is removed

The donor heart is removed.

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Adjacent theatre: surgeons prepare the recipient

Adjacent theatre: surgeons prepare the recipient

The heart transplant proceeds

The heart transplant proceeds

The first heart transplant represents a moment in medical history

The first heart transplant represents a moment in history

The first heart transplant represents a moment in history

Pause to imagine the human aspects

The father, who had just lost his wife in the same accident was losing his daughter (25 years old) and was now faced with an enormous request as a parent. Think about the decision, the success, then the feeling of loss again when LW subsequently died. Consider the impact on the father – and the rest of his family at the time and afterwards.

Plaque in memory of donor

Imagine the euphoria of the initial success – a dying man feeling alive again. As a precaution against rejection his immunity was suppressed – but then pneumonia took hold and he died 18 days after the operation. Think how this affected all those involved: the families, the surgical teams and care teams.

Subsequent events

This blog post covers a snapshot in time and place. There were controversies that continued for some time but they have been followed by major developments and successes. There have been significant advances in the field of heart transplantation in the past 40 years or so. More than 5000 heart transplants are now performed each year around the world.

—————

On this tour I had the pleasure of the company of a group of student nurses and doctors from the U.S. We were all touched by the experience of the tour. For me, the trip also rekindled an early childhood memory and stimulated some thoughts regarding current issues around breakthroughs in research.

The Heart of Cape Town Museum provides a unique experience of a moment in medical history and I recommend it to you all.

by Dr Julie Charlesworth 11/6/2015


[The photographs were taken by Julie Charlesworth and with permission, during the guided tour. The life-size models look so real and they are set in the actual operating theatres where the events took place.]

 

 
In Part 2 some other far-reaching issues of that time are highlighted together with some take home messages relating to breakthoughs in Life Sciences and medical research.

A Tree of Life Sciences® visits Groote Schuur Hospital, Cape Town, South Africa

Groote Schuur Hospital (Photograph taken 20th May 2015 by Julie Charlesworth)

Photograph taken 20th May 2015 by Julie Charlesworth

May 20th 2015 was International Clinical Trials Day and it seemed a very appropriate occasion to be visiting the Groote Schuur Hospital, which is also an internationally renowned research institution.

Groote Schuur is the main academic hospital for the University of Cape Town’s medical school. The hospital attracts visiting medical students, trainee doctors and specialists who go to gain further training and experience in various fields.

The hospital is also famous because it is the institution where the first human heart transplant was performed.

Out and about at the EMWA Conference

Last week A Tree of Life Sciences® director Dr Julie Charlesworth attended the European Medical Writers Association conference in Dublin from 5-9 May 2015.

Julie was participating in workshops and was also pleased to be invited again to lead a table of discussions for the EMWA Freelance Business Forum.

Julie says, “Thank you to EMWA for all the hard work in organising this event, which as usual was a great success”.

Big Pharma, Gobbledygook and Getting Real!

Reflect on the changes in Big Pharma, the future in Life Sciences is looking brighter – are we really ready for a fresh approach and changes in some of our business language?

I wrote on this very subject as an editorial for the 2015 Spring edition of the journal, Medical Writing.

Julie Charlesworth (Editorial) “Get Real: Avoiding corporate gobbledygook.”
Medical Writing 2015; 24(1), 23
DOI: 10.1179/2047480614Z.000000000273

Read here

Cancer News: Are two-thirds of cancers down to bad luck?

A Tree of Life Sciences Director gets stuck in to the debate about a recent controversial cancer publication, which received high-profile coverage in the media over the weekend (2–4 January 2015).

The cancer publication had widespread coverage in the press and on prime-time TV and radio news.

The study involved the application of mathematical models to data already in the published literature. A statistician was quick to respond in his blogpost, with criticism of some of the media coverage and questions regarding some claims in the actual publication.

An interesting on-line debate ensued involving statisticians, scientists, clinicians and journalists. A key question is – what proportion of cancers are really due to “bad luck,” that is, random mutations arising during DNA replication in normal, noncancerous stem cells? Our director Julie Charlesworth contributed points regarding cancer cell biology, and commented on wider perspectives such as the importance of patient and public awareness about cancer. She also called for continued vigilance about exposures to potential carcinogens and added that misinterpretation of new ideas should not ‘downplay’ the need for rigorous testing before widespread use of chemicals and new products.

A journalist suggested that ‘perhaps scientists interested in media accuracy can help reporters find informed and independent experts before their stories appear’ and the weekend discussion culminated in a proposal for ‘a New Year’s resolution for scientists and reporters to talk more’.

The publication in Science is very interesting. The findings merit further exploration in terms of causes, steps and mechanisms in cancer development. In addition the media coverage has stimulated discussion on wider issues relating to the interpretation and reporting of science.

The debates continue ………

Our website glossary is live

At A Tree of Life Sciences® we are committed to inclusion and to supporting non-native English speaking clients. That is why we have added a glossary to explain words and terms that can be difficult to understand.

English is a rich and evolving language, which we know from experience non-native English speaking people are keen to learn.

Click here to visit our glossary.

Click here to contact us if you wish to suggest a word or term to be added.

We look forward to seeing this section of our website grow organically and communally with you.

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