Happy International Clinical Trials Day!

It is International Clinical Trials Day – so just a few words to say there is much to celebrate in this area, particularly today! Thinking about the achievements resulting from clinical research.

– Thankful to all the people involved in clinical trials, particularly participants.

– Appreciating the dedicated work of professionals conducting and monitoring clinical trials; people researching new methods; researchers collaborating internationally.

– Pausing to reflect on the value of international clinical trials past and present.

Thinking about the future…

In the fields of clinical trial design, conduct, and reporting – we should celebrate the good and be critical of the bad/flawed. We need to continually seek to improve efficiency and standards.

by Dr Julie Charlesworth 20/5/22

[This date in May is chosen because it also ‘commemorates the day when James Lind started his famous clinical trial on scurvy in 1747, May 20th, and laid the foundation for modern clinical research.’]

MedComms, international medical publication professionals and medical writers.

Great to see MedComms, international medical publication professionals and medical writers engaging within their communities in conversations and discussions on what there is to be learned from the covid pandemic years. People have been working very hard in these fields. There is also much work to be done!

We should look positively to the future. Time to get on with making it a better future.

by Dr Julie Charlesworth 12/5/22

[Link to message early in the pandemic]

Proud of my registered company name and logo.

A Tree of Life Sciences®. I am proud of my registered company name and logo which I protect whenever necessary.

Logo | A Tree of Life Sciences Ltd
Through these themes I can continue to contribute to my mission to Inform, Improve and Inspire particularly in Life Sciences and health research; but also, in life and sciences more generally. My communications include papers, post, and poems.

Transcending borders and boundaries in subject and scope.

Global, national, and local projects or perspectives.

Project consultancy and communications. Life Sciences, Clinical and Health Research.

What a great time to be involved in research and communications!

by Dr Julie Charlesworth 30/4/22

[Serious with a creative flair. There is also a distinctive business card for A Tree of Life Sciences® which has been in circulation internationally and locally for many years. It continues to uniquely capture the essence of my company, my work and mission. Still loving the colour too.]

Moods, perspectives and plans.

2/4/22. Life feels grey and gloomy particularly in the news, but here’s hoping there may be light and blue skies to come. To new horizons.

A photo I took on 2 April 2022, that captures a moment and a mood.
To brighter times and a better future.

17/4/2022. Looking forward to walking through a ‘sea’ of bluebells soon. Life doesn’t always go to plan and sometimes we must just try and make the best of a situation and use our imagination…

Bluebell woods and me
Photo taken in May 2019 in a bluebell wood near to home in the UK. That’s me in the photo enjoying a magical moment in Nature’s Garden and a spot of ‘tree bathing’.

Getting out in Nature and a good dose of fresh air can help.

I hope it’s going to plan for you and if not, perhaps change the plans to try and stay positive.
Take care.
Happy holidays!

by Dr Julie Charlesworth 17/4/22

26/4/22 Update.
Home Sweet Home! Finally, home after my original plans to be back in the UK with family for the holidays were thwarted by covid. It’s still around – we need to take care of ourselves and others; and behave responsibly. Proceeding with caution. Take care.

Science transcends borders and boundaries.

Science transcends borders and boundaries. Collaboration is important in science. Open access to information is preferable. Truthful communication and transparent reporting are essential.

Integrity is key!

by Dr Julie Charlesworth 20/03/22

A few thoughts on International Women’s Day 2022.

For International Women’s Day let’s pause for thought. From a moment of reflection* now it is time for thoughts to the future. What kind of world do we want for future generations?

I am feeling a sense of humility.

In troubling times we can see the worst and the best of humanity.

Having recently welcomed a third grandchild I am reminded of the strength and resilience of women in particular new mothers.

To all the amazing women in many different fields who I feel proud to know. The very visible people and the quieter people all doing their bit in troubling times in a complex world.

Here’s to resilience, hope and positivity.

by Dr Julie Charlesworth 08/03/22

(* See the link to my previous IWD blog ‘A moment for reflection’)

An excellent experience at World Expo.

I had the opportunity to visit Expo 2020 during my recent visit to Dubai and I am excited to share some of my snapshots and observations. The original start date having been delayed by a year due to the Covid–19 pandemic could now proceed for 6 months from October 2021 to 31 March 2022, providing the world with some much-needed messages of happiness, resilience, hope and positivity.

World Expos occur every 5 years and this is the first ever to be held in the Middle East. Around 192 countries are represented. There are three core themes – namely Sustainability, Mobility and Opportunity. The motto of Expo Dubai is “Connecting Minds, Creating the Future”.

Some snapshots and highlights from a day’s visit to the Dubai Expo.

Welcome…
Welcome and Dubai Expo map

There is fun for all the family and for grown-ups, kids, or grandkids alike. For example: Featured in these snapshots are the enchanting ball pool experience in the Hungary pavilion; the Petit Prince theme in the France pavilion; the popular Water Feature outdoors.
Fun at Expo Dubai

Country Pavilions
Dubai Expo includes pavilions where different countries showcase their achievements in arts, culture, sciences, and business.

An impressive example is the UAE pavilion:

I was particularly drawn to the theme of Open Access to knowledge.
Open Access UAE pavilion

It was interesting to learn more about cutting edge research and innovative approaches in the UAE.
Research and innovation UAE

The vision and dreams for a better world were inspirational from a historical perspective and, also continued as a theme for the future.
Vision and dreams UAE pavilion

In summary, of course this short report is just a snippet of what there is to see and experience at the Dubai Expo. Combining a family outing with business and professional curiosity, and with young grandchildren in tow, our small family group made the most of a day visit from 10am to 4pm. We walked 10km! My only regret was I didn’t get to go back, spend more time there and explore more of the many exhibitions and events on offer.

Finally, to close here is a photo at dusk in Dubai.

Dusk in Dubai

If you get the chance, I recommend a visit to the Dubai Expo.

by Dr Julie Charlesworth 21/02/22

Rhubarb Rhubarb. Content Counts in Communications.

Content counts in communications – as illustrated in this short verse, a parody of meaningless content. In many arenas including science communications (and also of course in politics) we often hear the same old same old same old words, and they can merge into background crowd noise. Indeed, people may stop listening. I am posting this thought with a verse and a dollop of healthy scepticism to make a point 😉.

RHUBARB, RHUBARB ©
(A verse to be read aloud)

Rhubarb …

Rhubarb Rhubarb.

Rhubarb!

Rhubarb Rhubarb Rhubarb.

Rhubarb Rhubarb Rhubarb.

Rhubarb Rhubarb.

Rhubarb!

©Julie Charlesworth 2021

N.B. In theatre and film there is a practice of actors saying the word rhubarb repetitively to mimic the sound of indistinct conversation.

by Dr Julie Charlesworth 16/02/22

A good time for science, and gratitude.

It is actually a very good time for science! I am grateful to have been able to contribute over the years particularly in life sciences, clinical and health sciences; and to be part of the research communities. It is exciting work – there is much to be done and much to communicate.

I am also enjoying other interests including poetry – and being able to experiment there too!

I am grateful to my colleagues and friends in a range of disciplines and diverse areas. ‘Thank you’ to them for ‘keeping me on my toes’. I love exploring different perspectives and being able to appreciate contributions of others and to be able to contribute from a different and general viewpoint.

I love communication. I love poetry. It’s great to be able to experiment and hear of it being enjoyed by others too.

by Dr Julie Charlesworth 1/7/21

A quantum leap in my learning

There is a new technology that will impact society and the future of sciences: Quantum Technology. Oh, and did you know that apparently a quantum object can be in 2 places at the same time?

Context and background
In 2020 I participated in the EuroScience Open Forum (ESOF2020 Trieste). As in previous years not only did I check out some developments in my own specialisms and interests, but I also took the opportunity to get a flavour of some completely different areas.

I have prepared this short blog as a ‘taster’ to share my own ‘enlightenment’ with you and maybe to spark your curiosity.

Quantum technology has enormous potential. ‘It is expected that this will lead to an exponential growth in computing power, allow information to be communicated in an absolutely secure way and, again, allow measurements to be made with extreme precision.’

Some possibilities which were deemed science fiction in the past may become reality.

Computer power
Aspects of quantum computing are moving from the theoretical phase. We were told to watch out for big developments in the next 10 years or even in the next 5 years!

In classical or binary computing (i.e., the traditional approach) computers are said to perform calculations using “bits” of information. Like on-and-off switches, these exist in only two states: either 1 or 0. Quantum computers, however, use quantum bits, or “qubits,” which can exist as both 1 and 0 simultaneously!

To understand the potential of quantum computing requires a different way of thinking about information and also there are concepts that will be new to many people. An explanation provided in an expert panel discussion, at ESOF2020 helped me. This is the gist of it:

Consider the challenge of finding your way out of a very complex maze or labyrinth. With a classical computer you can think of a stepwise process choosing Left or Right until you find the right path. However, with a quantum computer you can explore all paths at once – can be likened to flushing a bucket of water through the labyrinth. That explanation was an ‘aha moment’ for me!

Elsewhere, I have heard that it is like ‘being able to read all the books in a library at once’. The speed and scope of this new technology viewed in this way becomes immediately more apparent to me.

What could the advantages be for users and citizens?

Here are examples of some potential and possible applications:

• Quantum simulation for use in the discovery and development of new drugs
• Quantum sensors and a role at the human brain interface e.g. potential for communication use maybe even for ‘locked-in syndrome’.
• Satellite navigation – the prospect of providing very accurate location.

Secure communications
Communication security is a top priority for governments around the world. There are some collaborations and there are also competitive aspects. The Chinese satellite, Micius, was launched in 2016 and recently reported a secure method of quantum messaging (published in Nature, 2020) which has generated interest. Other countries and regions are very interested in quantum satellites and are at various stages of research and development in this field.

The Italian ‘experiment’ at ESOF2020
The closing ceremony of the conference featured an ‘experiment’; the first Italian public demonstration of encrypted communication using Italian-made optical-fibre quantum technology. Participants and attendees were able to witness the capability of the technology and its ability to detect and prevent attempted ‘hacking’.

Europe is equipping itself with a quantum communication network called EuroQCI, which includes optical-fibre cables and satellites. Italy is at the forefront of this field.

Beyond Trieste
After the ESOF conference I felt it was time for some consolidation of what I was learning. If this is a new subject for you and you want to learn more you will encounter new concepts and new terms such as repeaters, entanglement etc. We need a better understanding of terminologies and basic physics. Of course, there will be many sources of further information. I have provided examples of videos I found helpful (see below).

Phases and progress of quantum technology: Where are we now?
Different aspects of quantum technologies are at different points in this path:

Research → Development → Innovation

Discoveries will be made and facilitated by new investments and collaborations including academia and industry. There is already a lot of knowledge in Europe (and Italy is ‘a big player’ in Europe).

It is a promising field where some things are coming already, or some things may come soon, and there are some things where there are still major challenges.

There are likely to be exciting breakthroughs but also disappointments. There will definitely be A NEED FOR HYPE CONTROL!

Call to action
Do not worry if you find this subject challenging to understand, many people do. It is OK to be still grappling with some of the ideas and terms. I am told even many physicists feel the same way. Working through the confusion is how we learn. Writing this blog helped me and I hope reading it helps you.

Be curious.

A small brave step could lead to a quantum leap in your understanding on many levels.

I hope sharing my learning is useful to others.

by Dr Julie Charlesworth 26/1/21

Further information:

Recent publication about the Chinese satellite (Nature, 2020)
Yin, J., Li, YH., Liao, SK. et al. Entanglement-based secure quantum cryptography over 1,120 kilometres. Nature 582, 501–505 (2020). https://doi.org/10.1038/s41586-020-2401-y

Videos I found helpful:
Quantum Computers Explained – Limits of Human Technology
Kurzgesagt – In a Nutshell. You Tube

If You Don’t Understand Quantum Physics, Try This!
DoS- Domain of Science. You Tube

A big thank you to ESOF2020 for the opportunity to learn about quantum technology.
I have written several previous posts about ESOF2020 for example here